Descartes And God Essays - Epistemology, Ren Descartes, Free Essays

Descartes And God Essays - Epistemology, Ren Descartes, Free Essays Descartes And God Jared Rhine English 201 October 10, 1997 Descartes sets about proving the existence of God through his meditations on knowledge in an effort to prove the skeptics of his time wrong. He first determines that human knowledge is based entirely too much on unproved presuppositions. He argues that this makes it difficult to distinguish between truth and error, since we cannot recognize true knowledge. Descartes proposes that the quest for knowledge must be based upon universal doubt. Specifically, he proposes the following in relation to his universal methodic doubt: 1. In order to seek truth, it is necessary once in the course of our life, to doubt, as far as possible, of all things. 2. We ought also to consider as false all that is doubtful. 3. We ought not meanwhile to make use of doubt in the conduct of life 4. Why we may doubt of sensible things. 5. Why we may also doubt of mathematical demonstrations. 6. We cannot doubt of our existence while we doubt, and this is the first knowledge we acquire when we philosophize in orde r. Descartes proceeded to strip away his knowledge base in order to determine the one indubitable fact, Cogito, ergo sum. From this absolute knowledge of his own existence, he set about deducing the existence of God through ontological argument. In our minds, the idea of God is one of an infinitely perfect Being. An infinitely perfect being must have existence, otherwise it would not be infinitely perfect. Therefore, God exists. In proving the existence of God, Descartes set the groundwork for determining that God created man. He further postulated that God, being infinitely perfect and not a deceiver, could not have provided man with the deceptive powers of knowledge. Therefore, man's mental faculties are determined to be trustworthy provided we separate what there is of clear and distinct in the knowledge from what is obscure and confused. Using this reasoning, man must discard all previous knowledge, which is doubt-ridden, all sensory-based knowledge (as perceptions can be misleading ), and all intellection. As a result, skepticism is removed and valid knowledge possible. Descartes primary purpose was the defense of human knowledge against the attacks of the skeptics. He was justified in excluding preconceived notions, presuppositions, and traditions in determining the limits of knowledge. Descartes discarded the ability of the mind to know truth and the human abilities of contradiction and sufficient reason. In doing so, he made a solution to the problem impossible. As it relates to his theory of the existence of God, Descartes universal doubt refutes his own conclusion as to God's existence. Descartes formed an idea of God as an infinitely good being. He would have had to discover this idea within his own mind. According to his principle of universal doubt, he cannot simply know whether his conception of God is correct or incorrect. He would have, as a matter of his own principle, considered it as false until proven otherwise. Therefore, since the idea of God is in doubt, the trustworthiness of man's reasoning must also be doubtful and Descartes cannot escape his own real doubt. Descartes uses a process of reasoning, a mathematical formulae, in attempting to demonstrate God's existence. If his reasoning is of demonstrably doubtful validity, how can Descartes demonstrate God's existence? The validity of Descartes reasoning is supposed to flow as a consequence of the infinite perfection of God; and God's infinite perfect is made certain through Descartes' reasoning powers before he has even proven that these reasoning powers are valid and trustworthy. Descartes assumes the very thing beforehand, which he intends to prove afterwards. Descartes accepts the trustworthiness of his faculties in demonstrating the existence and infinite perfection of God, and that is illegitimate. A doubtfully valid faculty will produce a doubtfully valid argument, which will, in turn, produce a doubtfully valid conclusion. The ent ire argument for God's existence is therefore nullified by a suspect reasoning process. Since he proves the reliability of his reason and process by means of God's veracity, the proof of his reliability cannot be established beyond doubt. Thus, Descartes attempt to vindicate the validity of human knowledge failed, because, by rejecting the reliability of his own powers to discover and know

9 Career Options for Business Majors

9 Career Options for Business Majors If youll be graduating soon with a degree in business (or are considering getting one), its safe to say you have a lot of job options. But youll also have a lot of competition: Business degrees are by far the most popular bachelors degrees in the United States. That being said, the reason business degrees are so popular is because theyre applicable in a wide variety of industries, and the skills you acquire on the way to earning a business degree likely make you a versatile employee. No matter what job you want, you can probably make the case that your business education gave you the skills you need to succeed. As far as the more traditional business careers go, here are some of the top jobs worked by people who majored in business. 14 Careers for Business Majors 1. Consulting Working for a consulting company can be a great place to start if you know youre interested in business but arent sure what sector youre most interested in. Businesses bring in consulting firms for an outside perspective to help solve a problem, whether thats a problem with finance, management, efficiency, communication or something else. Consulting will let you see all kinds of industries, and you can probably find a position suited to your particular skills. 2. Accounting Working at an accounting firm will help you understand the gritty details of a business. Like any firm, you can pursue more of a management track, or you could get into the bread and butter of the business: number crunching. Youll likely need a concentration in accounting or take the certified public accountant test. 3. Financial Planning Interested in investing? Helping people prepare for retirement? Consider working at a financial planning firm. This career also often requires taking certification tests, as well. 4. Investment Management Working at an investment firm can give you a unique insight into some of the most exciting, up-and-coming companies as well as how they work. Those with a background in economics may be best suited for this career, as it requires interpreting the economic impact of current events, understanding their nuances and having a grasp on investment trends. 5. Non-Profit Management Most people think of business degrees as a great way to make money. But working for a non-profit is a great way to make a salary while also helping out those who are working toward a larger social cause. After all, non-profits need smart managers who can make the most of limited resources. 6. Sales While business degrees often require a firm grasp on numbers, they also focus on developing communication skills. A sales role requires both. You can find a sales role in almost any company, so choose something that interests you. Be prepared for work thats very goal-oriented and requires a self-starter attitude. 7. Marketing and Advertising You cant have a successful business if youre not reaching your customers. Thats where marketing comes in. Marketing is a collection of all activities to promote a product, company or thing. This industry needs both business-focused and creative minds, and you can do this work in a dedicated department of a company or as an outside consultant. 8. Entrepreneurship You know the basics of business- why not start your own? Its certainly not easy, but if you have a passion for something and can develop a sound plan for getting it started, you may have what it takes to build your own company. 9. Fundraising or Development People who are good with money are often good at helping other people donate money. Consider working in fundraising or development and challenging yourself in all kinds of interesting ways. Other Ideas You can make your business degree relevant to careers well beyond this list. Consider your interests and how you might apply your business acumen in such a field. If, for example, you are passionate about writing and the environment, consider blending all of your interests in one job- like working on the business end of an environmental magazine or website.

International relation's discussion Assignment Example | Topics and Well Written Essays - 250 words

International relation's discussion - Assignment Example ny, without doubt is a bad person that should be captured and face charges of crime against humanity at the international criminal courts, but his capture would come with other consequences, which might prove to be disastrous. In that case, peace and reconciliation techniques should be used especially in Northern Uganda to avoid any kind aggression between the rebels and government forces. Another key factor is African matters should be dealt by African people. There is absolute no need for putting pressure on the United States government to intervene (Peter, 21). As much as African countries appreciates the wet support in terms of foreign aid and donation they have also proved to the world that they are willing and ready to solve their own problems, some which have proved to be big challenges to the world. Therefore, the campaign for western countries to intervene in Kony’s capture is very not a good idea. The realist will not agree with the idea of going all out to capture Joseph Kony. This is because there are still other ways of coming up with a good solution to that problem. Still there are treaties between counties that must be respected. Kony is believed to have left Northern Uganda for South Sudan or Central African Republic, so attempt for invasion on Northern Uganda will be only cause harm to the healing

The Perfect Husband Essay Example | Topics and Well Written Essays - 500 words

The Perfect Husband - Essay Example As I mature, I realized that perfection can be seen on how a husband is someone who understands and provides a woman's needs and how he keeps his marital commitment, how displays sacrificial leadership. A woman and a man have different needs which should be met by their lifetime partners. A perfect husband should be able to differentiate from his needs and his wife's needs and respond to them. For example, it is stressed that while a man's primary motivation for marriage is sexual fulfillment, a woman constantly longs for his husband's affection and love. Thus, a husband should always show his love to the wife by doing small things like sending her love notes, cooking for her, hugging her a lot, and telling her how much she means to him. A perfect husband is someone who will never think twice of giving up his machismo and show his soft side in order to satisfy his wife. He will also go the extra mile in order to show his constant love and affection. Secondly, a husband should have a strong marital commitment. It is irrefutable that most men detest commitment and dedication but a perfect husband is someone who reaches the maturity of being accountable and responsible for his actions. Since he allowed himself to be bound by a lifetime commitment, he will make sure that he stays faithful to his wife. When the going gets tough, he stays with the wife and remains devoted to her. The husband is often regarded as a head of the family even in this more

History of DNA Sequencing and Research

History of DNA Sequencing and Research DNA sequencing technology has evolved very rapidly since its inception in the 1970s, and continues to evolve and grow today. This paper will review the major innovations and developments in sequencing technology and briefly summarize their methodologies. The first group that was able to sequence DNA was the team of Allan Maxam and Walter Gilbert (Maxam and Gilbert). This was a first generation sequencing reaction, and was developed in 1976-1977. This method uses purified DNA and relies on chemical modification of DNA bases (like depurination of adenine and guanine using formic acid and methylation using hydrazine or dimethyl sulfate). The 5 end is radioactively labeled so that it can be visualized in a gel, and then fragments of modified DNA are electrophoresed. Autoradiography can then be used to visualize the sizes of each DNA fragment. The maximum read length for this technique was approximately 100 bases long. The next major innovation in DNA sequencing was the Sanger dideoxy chain termination method. This was developed in 1977 by Frederick Sanger (Sanger, Nicklen, and Coulson), and became much more popular than Maxam and Gilberts method. Sanger sequencing is a synthesis reaction and uses dideoxy nucleotides to randomly terminate synthesized strands of DNA. The DNA strands that had been terminated with ddNTPs originally were run in 4 different lanes (one for each ddNTP) and were radiolabeled so that they could be visualized with autoradiography. Later innovations made Sanger sequencing even easier when each dideoxynucleotide was labeled with different fluorescent dyes. As such, sequences could be run on a single gel in a single lane. This method was the most popular way of sequencing DNA for many years, and was prevalent until about 2004. While read length was initially about 100 base pairs long, Sanger sequencing now has a read length of about 800 to 1000 base pairs long when run in capil lary gels. With the start of the human genome project, it was necessary to find ways to sequence DNA much more quickly and more cost-effectively than had been done previously. This led to the development of so-called à ¢Ã¢â€š ¬Ã…“second generationà ¢Ã¢â€š ¬Ãƒâ€šÃ‚  DNA sequencers. It also allowed for the use of smaller samples for sequencing. One of the first major automated platforms was the Roche 454 (Margulies et al.). This utilizes pyrosequencing, which is a synthesis type sequencing reaction. This also uses emulsion PCR on beads. When a dNTP is incorporated, it releases a pyrophosphate (PPi). ATP sulfurylase is present in the reaction mix, and when PPi is released, converts it to ATP, which can activate luciferase and the emission of light. The Roche 454 can measure the amount of light given off and relate it to the number of nucleotides that have been incorporated. One problem with this type of sequencing is that it can be difficult to accurately characterize sequences of the same nucleotide in a row as the intensity of the pyrophosphate peak given off does not have a linear relationship with the number of homopolymers present. The read length for 454 is approximately 250 base pairs long, and the error mode tends to have indels. The next major second gen sequencer is the Illumina Solexa platform (Bennett). The chemistry of this platform is that it utilizes reversible terminators and sequences by synthesis. A flow cell is covered with DNA oligonucleotides that are complementary to adaptor sequences that have been ligated to the ends of fragmented genome pieces. As the genome fragments are streamed across the surface of the flow cell, they will randomly bind and go through multiple cycles of denaturation and extension, which creates clusters of clones. After these clusters have been generated, they are loaded into a sequencer which measures fluorescent signals as single nucleotides are incorporated by taking a picture and noting the location of fluorescence. Read lengths are about 26-50 bases on average, and the types of errors that are typically present tend to be SNP errors. Another important second generation sequencer is the ABI-SOLiD (Sequencing by Oligonucleotide Ligation and Detection) sequencing platform (Valouev et al.). This is another sequencing by synthesis reaction, but unlike Illumina and 454, which use polymerases, this uses ligases. After using emulsion PCR on beads to create clonal clusters, primers base pair to a known adapter sequence that has been ligated to the genomic DNA. Differently labeled probes competitively base pair to the sequencing primer, and sequencing goes through several cycles in which different primers are used each time to bind to positions offset by a single nucleotide each time. DNA bases are added in groups of two in this method. Average read lengths for this technique are on average about 35 base pairs long. The next second generation sequencing technique is Ion Torrent, which is a sequencing by synthesis technique (http://www.iontorrent.com). When nucleotides are added to a growing DNA chain, pyrophosphate and a hydrogen ion are released. Ion Torrent takes advantage of this by measuring the pH of the reaction mix after flooding a DNA strand with the four bases (one at a time) to determine sequences. One major advantage of this technique is that it doesnt require a high-cost camera set-up to measure incorporation events. However, because it indirectly measures nucleotide addition through changes in pH, it has difficulty with accuracy in calling sequences of homopolymers, resulting in indel errors (like pyrosequencing). Average read lengths using this technique are about 200 base pairs long. A more recent innovation is the Helicos-True Single Molecule Sequencing (tSMS) technique (Thompson and Steinmann). It is somewhat similar to Illumina sequencing in that it also uses fragmented DNA, adaptors, and fluorescently labeled dNTPs, but there is no amplification step. This helps eliminate issues with GC bias, which tend to affect amplification steps and can cause errors in base calling. Average read length is greater than 25 base pairs. Pacific Biosciences SMRT technology (Single Molecule Real Time sequencing) immobilizes a DNA polymerase at the bottom of a well and is a sequencing by synthesis technique (Eid et al.). Fluorescently labeled phosphate groups in dNTPs are added to the reaction mix and as the base is added to the growing DNA strand, the machine can measure the light that is given off (each base is labeled with a different fluorescent molecule). The major advantage of this technique is that it can sequence very long reads (more than 1000 bp!) which is very important in de novo sequence assembly. In addition, PacBio can also measure methylation of DNA sequences based on the kinetics of addition of base pairs (using the observation that modified base pairs tend to take longer to incorporate into a DNA strand). Furthermore, this technique can also potentially use a single molecule of DNA, which reduces any GC bias that occurs due to amplification. The final technique that will be discussed here is nanopore sequencing (Stoddart et al.). The idea behind this is that DNA may be threaded through a nanopore one base at a time. As its fed through, the sequencer can measure the change in current as it passes through (which will vary based on what base is moving through the pore). Thus, the sequence can be determined straight from the DNA without the need for modifications or reagents. In addition, because this can be done on a single molecule, there is again no need for amplification and thus no possibility of any GC bias in base calls.

Playing God in Today’s World Essay

The two fictional characters who â€Å"play God† in their own lives are two doctors, one of philosophy (Faustus) and one of medicine (Frankenstein) and, in real life, it is anyone who takes power over another’s and one’s own life and makes up his/her own rules which go against the commandments given to us by God as the athlete Lance Armstrong did during many years. First, there is Dr. Faustus, a very famous and successful scholar. He is a smart man who knows everything about almost all sciences in the world, including philosophy, theology, law, and medicine. Yet, this knowledge is not enough for him. He is greedy and obsessive about it and the more he learns, the more he desires. Soon, all that he knows makes him extremely bored; there is only one science that gives him excitement – magic. â€Å"These books by magicians- lines, circles and mysterious drawings- Yes, these are the books that I enjoy the most. Oh, what a world of power and reward they promise the hard-working student! With this knowledge, I’ll be the master of everything that moves on Earth†¦ this is your answer Faustus. Use your brain to become a god† (Marlowe 22). Faustus is willing to do anything to be the greatest in this field, so he decides to sign an agreement with the Devil and give him his soul in exchange for 24 years of magical talents and power over life itself. After this agreement is set, Faustus gets all the unimaginable power in life; learns all that he wants about this forbidden science; brings people back to life, and earns worldwide admiration and recognition for his work. Nevertheless, none of these God-like powers and tricks of magic bring him happiness. Deep in his heart he knows he is doing wrong and he will be damned forever. At last, he ends his days being lonely and is punished forever in hell. Clearly, Faustus tries to play God, but at the end, the only thing he does is to bring God’s anger upon himself. â€Å"With paper wings he flew too near the sun and heaven planned his downfall† (epilogue). Secondly, there is Victor Frankenstein, a man who has everything he needs plus a very happy family. He is a great man, who is dedicated to his studies and very clever, but he makes the same mistake as Faustus did. He plays God by trying to discover the secrets of life, and when he does, he uses them the wrong way. When his mother dies, he has to leave his sad family and go to university to study medicine. There, he becomes obsessed with the idea of knowing â€Å"the secret of life† and how to help others not to feel the sorrow he and his family did because of the loss of a loved one. Soon, after much study about death and life, he finds the answer to all the questions in his head and starts to develop a horrible project. â€Å"He takes parts from dead people and builds a new ‘man’. But this monster is so big and frightening that everyone runs away from him – even Frankenstein himself! (Comment by editor). Victor is so terrified of his own creation that the only thing he wants is to escape from it so, irresponsibly; he abandons his laboratory and the monster, which has no idea of how to speak, survive, or live. †The monster is like an enormous baby who needs love. But nobody gives him love, and soon he learns to hate. And because he is so strong, the next thing he learns is how to kill† (Comment by editor). The monster is full of resentment and decides to make Frankenstein just an unhappy and lonely as he has been his entire life. He kills all people Frankenstein loves and makes Victor look forward only to the day that he can be dead and together with his family. Clearly, Frankenstein tries to play God, but at the end, the only thing he does is to bring unhappiness and misery to his life and his loved ones’. Finally, there is Lance Armstrong, a successful and rich cyclist who has won the Tour De France seven consecutive times. He has a lot of fans around the world and is considered a strong and admirable man by many people. However, after years of arduous denials and attacks on any person who has questioned his clams of competing clean, he has been proved to use performance-enhancing drugs since 1998. Now, he is disqualified from all his titles since that year and banned from professional cycling for life. Fans, friends, and family have gone away from him and now he is left only with the money that he has made, but today this does not seem to make him happy. He did a lot of mistakes through his career and personal life and used his cancer to justify them to himself. My cocktail, so to speak, was only EPO, not a lot, [blood] transfusions and testosterone, which I almost justified because of my history. Obviously, the testicular cancer and losing [a testicle], [I] thought, surely I’m running low. †(Armstrong’s interview with Oprah). The first mistake that he makes is to forget about his spiritual values and to start violating God’s law. Victory becomes his obsession and he is wi lling to obtain it at all costs. He is not only loosing his soul, but also damaging his body and reputation. Moreover, he has given false witness in front of millions of people and fooled everyone who believes in him. Again in this case, it is clearly illustrated how â€Å"playing God† can destroy someone’s life. Considering all the above, it is evident how obsessions can lead people to self-destruction. Armstrong, Frankenstein, and Dr. Faustus have made up their own rules and ways of living, according to what they want and not caring about how they are damaging themselves and the ones around them. They are all men of successes until God decides that it’s time to pay for the mistakes they have done; and at that point, it is too late to repent. The three of them have forgotten that life is not about what we accomplish, but about the way we do it.

The Effects Urbanisation Is Having on Australias...

Today, this briefing note is put to you the National Taskforce on Environmental Science and Sustainable Development in response to Urbanisation and its effects on Australias’ waterways. This is fast becoming a critical environmental issue affecting Australia. It has long been known that plants act as a natural filter of water, removing all the properties that would harm the creatures that ingest it. A key issue facing developers today is an expanding population. With expanding urban sprawl vastly affecting the green space urban development, strategies continue to focus on removing the encroachment of land as a development strategy and going ‘up’. This essay will focus on the eutrophication of waterways within Australia and in†¦show more content†¦Ammonium is the form of nitrogen taken up most readily by phytoplankton because nitrate must first be reduced to ammonia before it is assimilated as amino acids in organisms (Geoscience Australia, 2013). The excessive level of certain nutrients in waterways is often linked to human activities. A comprehensive investigation on how nutrients in waterways were increasing, was undertaken by a body of individual scientists and their findings were as follows; - Run-off from agricultural areas; - Storm water and wastewater; - Turbidity and nutrient levels occur within Australia’s river systems, generally coincide in Australias river systems. A large proportion of the suspended sediment in Australian rivers results from vegetation removal, leading to gully and stream bank erosion and sheetwash. Phosphorus is overwhelmingly associated with such particulate loads (The National Land and Water Resources Audit, 2002). - Dentrification is a major sink for inorganic nitrogen in estuaries. Nitrogen loss due to denitrification can exceed 50% of the total nitrogen input, and is probably the main reason why nitrogen can sometimes be the limiting nutrient in estuaries (Berelson, W.M., Heggie, D., Longmore, A., Kilgore, T., Nickolson, G., Skyring, G. 1998). - Water column phosphorus concentrations have also been shown to increase under anoxic conditions (Webb, K.L. and DElia, C.F. 1980). This is because some of the iron oxyhydroxides that